Correlation Between Decrease in Protein Levels of Ubiquitin Ligase HRD1 and Amyloid-β Production
Endoplasmic reticulum-associated degradation (ERAD) is a quality control mechanism in which unfolded proteins are retro-translocated to the cytosol for degradation. Our recent study showed that suppression of expression of ubiquitin ligase HRD1, which is involved in ERAD, caused amyloid precursor pr...
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Main Authors: | Ryo Saito (Author), Masayuki Kaneko (Author), Yasunobu Okuma (Author), Yasuyuki Nomura (Author) |
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Format: | Book |
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Elsevier,
2010-01-01T00:00:00Z.
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