Sevoflurane Increases Hippocampal Theta Oscillations and Impairs Memory Via TASK-3 Channels

• Main Authors: Linlin Han (Author), Shuai Zhao (Author), Feng Xu (Author), Yafeng Wang (Author), Ruihui Zhou (Author), Shiqian Huang (Author), Yuanyuan Ding (Author), Daling Deng (Author), Weike Mao (Author), Xiangdong Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sevoflurane can induce memory impairment during clinical anesthesia; however, the underlying mechanisms are largely unknown. TASK-3 channels are one of the potential targets of sevoflurane. Accumulating evidence supports a negative role of intracranial theta rhythms (4-12 Hz) in memory formation. He...