Local Drug-Induced Modulation of gp130 Receptor Signaling Delays Disease Progression in a Pig Model of Temporo-Mandibular Joint Osteoarthritis

• Main Authors: Nancy Q. Liu (Author), Shuo Chen (Author), Dawei Geng (Author), Jie Lei (Author), Jiankang Zhang (Author), Liangliang Li (Author), Yucheng Lin (Author), Yuxin Ouyang (Author), Ruzanna Shkhyan (Author), Ben Van Handel (Author), Fangzhou Bian (Author), Tadiwanashe Mkaratigwa (Author), Yang Chai (Author), Denis Evseenko (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Temporomandibular joint disorders (TMJs) are a multifaceted group of chronic disorders characterized by stiffness in the jaw, limited jaw mobility and pain when opening or closing the mouth. TMJs are relatively common, with incidence rates in the range of 5-12%, with nearly twice as many women as me...