Safety, Tolerability, and Pharmacokinetics of a Novel Mitochondrial Modulator, TRC150094, in Overweight and Obese Subjects: A Randomized Phase-I Clinical Trial

• প্রধান লেখক: Deepa Joshi (লেখক), Prashant Jamadarkhana (লেখক), Suchit Kumbhare (লেখক), Amarinder Singh (লেখক), Jignesh Kotecha (লেখক), Deepak Bunger (লেখক), Ajay Shiwalkar (লেখক), Anookh Mohanan (লেখক), Chaitanya Dutt (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

TRC150094, a novel mitochondrial modulator, can restore metabolic flexibility by improving insulin resistance in preclinical studies. This study primarily aims to evaluate the safety, tolerability, and pharmacokinetics (PK) of oral TRC150094 after conducting two double-blind, randomized, Phase-I stu...