Safety, Tolerability, and Pharmacokinetics of a Novel Mitochondrial Modulator, TRC150094, in Overweight and Obese Subjects: A Randomized Phase-I Clinical Trial

• Hauptverfasser: Deepa Joshi (Verfasst von), Prashant Jamadarkhana (Verfasst von), Suchit Kumbhare (Verfasst von), Amarinder Singh (Verfasst von), Jignesh Kotecha (Verfasst von), Deepak Bunger (Verfasst von), Ajay Shiwalkar (Verfasst von), Anookh Mohanan (Verfasst von), Chaitanya Dutt (Verfasst von)
• Format: Buch
• Veröffentlicht: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Schlagworte: article
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TRC150094, a novel mitochondrial modulator, can restore metabolic flexibility by improving insulin resistance in preclinical studies. This study primarily aims to evaluate the safety, tolerability, and pharmacokinetics (PK) of oral TRC150094 after conducting two double-blind, randomized, Phase-I stu...