Safety, Tolerability, and Pharmacokinetics of a Novel Mitochondrial Modulator, TRC150094, in Overweight and Obese Subjects: A Randomized Phase-I Clinical Trial

• मुख्य लेखकों: Deepa Joshi (लेखक), Prashant Jamadarkhana (लेखक), Suchit Kumbhare (लेखक), Amarinder Singh (लेखक), Jignesh Kotecha (लेखक), Deepak Bunger (लेखक), Ajay Shiwalkar (लेखक), Anookh Mohanan (लेखक), Chaitanya Dutt (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

TRC150094, a novel mitochondrial modulator, can restore metabolic flexibility by improving insulin resistance in preclinical studies. This study primarily aims to evaluate the safety, tolerability, and pharmacokinetics (PK) of oral TRC150094 after conducting two double-blind, randomized, Phase-I stu...