Safety, Tolerability, and Pharmacokinetics of a Novel Mitochondrial Modulator, TRC150094, in Overweight and Obese Subjects: A Randomized Phase-I Clinical Trial

• Những tác giả chính: Deepa Joshi (Tác giả), Prashant Jamadarkhana (Tác giả), Suchit Kumbhare (Tác giả), Amarinder Singh (Tác giả), Jignesh Kotecha (Tác giả), Deepak Bunger (Tác giả), Ajay Shiwalkar (Tác giả), Anookh Mohanan (Tác giả), Chaitanya Dutt (Tác giả)
• Định dạng: Sách
• Được phát hành: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

TRC150094, a novel mitochondrial modulator, can restore metabolic flexibility by improving insulin resistance in preclinical studies. This study primarily aims to evaluate the safety, tolerability, and pharmacokinetics (PK) of oral TRC150094 after conducting two double-blind, randomized, Phase-I stu...