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Rhubarb Enema Decreases Circulating Trimethylamine N-Oxide Level and Improves Renal Fibrosis Accompanied With Gut Microbiota Change in Chronic Kidney Disease Rats

Objectives: Trimethylamine N-oxide (TMAO), a metabolic product of gut flora, is increased in chronic kidney disease (CKD) subjects and is recognized as one type of uremic toxins which is associated with poor cardiovascular outcomes and kidney function loss. Previous studies have suggested that rhuba...

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Main Authors: Chunlan Ji (Author), Yin Li (Author), Yenan Mo (Author), Zhaoyu Lu (Author), Fuhua Lu (Author), Qizhan Lin (Author), Xusheng Liu (Author), Chuan Zou (Author), Yuchi Wu (Author)
Format: Book
Published: Frontiers Media S.A., 2021-12-01T00:00:00Z.
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