MKRN3 and KISS1R mutations in precocious and early puberty

• Main Authors: Sara Pagani (Author), Valeria Calcaterra (Author), Gloria Acquafredda (Author), Chiara Montalbano (Author), Elena Bozzola (Author), Pietro Ferrara (Author), Manuela Gasparri (Author), Alberto Villani (Author), Mauro Bozzola (Author)
• Format: Book
• Published: BMC, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Pubertal timing is known to be influenced by interactions among various genetic, nutritional, environmental and socio-economic factors, although the ultimate mechanisms underlying the increase in pulsatile GnRH secretion at puberty have yet to be fully elucidated. The aim of our...