Fenofibrate-promoted hepatomegaly and liver regeneration are PPARα-dependent and partially related to the YAP pathway

• Principais autores: Shicheng Fan (Autor), Yue Gao (Autor), Pengfei Zhao (Autor), Guomin Xie (Autor), Yanying Zhou (Autor), Xiao Yang (Autor), Xuan Li (Autor), Shuaishuai Zhang (Autor), Frank J. Gonzalez (Autor), Aijuan Qu (Autor), Min Huang (Autor), Huichang Bi (Autor)
• Formato: Livro
• Publicado em: Elsevier, 2024-07-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Fenofibrate, a peroxisome proliferator-activated receptor α (PPARα) agonist, is widely prescribed for hyperlipidemia management. Recent studies also showed that it has therapeutic potential in various liver diseases. However, its effects on hepatomegaly and liver regeneration and the involved mechan...