Generation of Retinal Organoids with Mature Rods and Cones from Urine-Derived Human Induced Pluripotent Stem Cells

• Main Authors: Guilan Li (Author), Bingbing Xie (Author), Liwen He (Author), Tiancheng Zhou (Author), Guanjie Gao (Author), Shengxu Liu (Author), Guangjin Pan (Author), Jian Ge (Author), Fuhua Peng (Author), Xiufeng Zhong (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Urine cells, a body trash, have been successfully reprogrammed into human induced pluripotent stem cells (U-hiPSCs) which hold a huge promise in regenerative medicine. However, it is unknown whether or to what extent U-hiPSCs can generate retinal cells so far. With a modified retinal differentiation...