Necrotizing enterocolitis leads to disruption of tight junctions and increase in gut permeability in a mouse model

• Main Authors: Srikanth Ravisankar (Author), Rodney Tatum (Author), Parvesh M. Garg (Author), Maja Herco (Author), Prem S. Shekhawat (Author), Yan-Hua Chen (Author)
• Format: Book
• Published: BMC, 2018-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Necrotizing enterocolitis (NEC) is a leading cause of death in preterm infants. Neonates weighing <1500 grams are at the highest risk for acquiring NEC, with a prevalence of nearly 7-10%, mortality up to 30%, and several long-term complications among survivors. Despite advance...