A novel hyaluronidase from brown spider (Loxosceles intermedia) venom (Dietrich's Hyaluronidase): from cloning to functional characterization.
Loxoscelism is the designation given to clinical symptoms evoked by Loxosceles spider's bites. Clinical manifestations include skin necrosis with gravitational spreading and systemic disturbs. The venom contains several enzymatic toxins. Herein, we describe the cloning, expression, refolding an...
Saved in:
Main Authors: | Valéria Pereira Ferrer (Author), Thiago Lopes de Mari (Author), Luiza Helena Gremski (Author), Dilza Trevisan Silva (Author), Rafael Bertoni da Silveira (Author), Waldemiro Gremski (Author), Olga Meiri Chaim (Author), Andrea Senff-Ribeiro (Author), Helena Bonciani Nader (Author), Silvio Sanches Veiga (Author) |
---|---|
Format: | Book |
Published: |
Public Library of Science (PLoS),
2013-01-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Inhibition of Tityus serrulatus venom hyaluronidase affects venom biodistribution.
by: Bárbara Bruna Ribeiro de Oliveira-Mendes, et al.
Published: (2019) -
Structure-based virtual screening to predict Loxosceles spider venom natural inhibitors
by: Haitham Ahmed Al-Madhagi
Published: (2023) -
Sphingomyelinases D From Loxosceles Spider Venoms and Cell Membranes: Action on Lipid Rafts and Activation of Endogenous Metalloproteinases
by: Priscila Hess Lopes, et al.
Published: (2020) -
Targeting Loxosceles spider Sphingomyelinase D with small-molecule inhibitors as a potential therapeutic approach for loxoscelism
by: Priscila Hess Lopes, et al.
Published: (2019) -
Molecular, immunological, and biological characterization of Tityus serrulatus venom hyaluronidase: new insights into its role in envenomation.
by: Carolina Campolina Rebello Horta, et al.
Published: (2014)