Chapter 3 Challenges and opportunities for optochemical genetics

• Main Author: Isacoff, Ehud Y. (auth)
• Other Authors: Kramer, Richard H. (auth), Trauner, Dirk (auth), Hegemann, Peter (Editor), Sigrist, Stephan (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Berlin/Boston De Gruyter 2013
• Subjects: Biophysics; Genetics (non-medical); Neurosciences; Human biology; Genetic Engineering; Neuroscience; Optics; Vision Restoration
• Online Access: OAPEN Library: download the publication; OAPEN Library: description of the publication

The transmembrane proteins that underlie neural processing are now known at a level of detail that has greatly increased our understanding of these sophisticated molecular machines. Starting with MacKinnon's seminal structure of a potassium channel, several voltage-gated ion channels and ionotr...