Chapter 11 Metabolomics in the Analysis of Inflammatory Diseases

• Autor principal: Clay, Elizabeth (auth)
• Outros Autores: Kapoor, Sabrina (auth), Bayley, Rachel (auth), Wallace, Graham R. (auth), Young, Stephen P. (auth), Fitzpatrick, Martin (auth), R., Graham (auth), P., Stephen (auth)
• Formato: Recurso Electrónico Capítulo de Livro
• Idioma: inglês
• Publicado em: InTechOpen 2012
• Assuntos: Biochemistry; molecular biology; biochemistry; genetics; Hypoxia (medical); Inflammation; Lactic acid; Metabolism; Metabolite; Metabolomics; Rheumatoid arthritis
• Acesso em linha: OAPEN Library: download the publication; OAPEN Library: description of the publication

Resumo

Most infections and traumatic injuries are cleared or repaired relatively rapidly and metabolic homoeostasis is soon restored. However, there is a broad range of inflammatory diseases which involve chronic activation of the immune system and, as a result, chronic persistent inflammation. We have been studying the metabolic consequences of chronic inflammatory diseases with the aim of identifying metabolic fingerprints which may provide clues about why the localised tissue disease persists.

ISBN

31814

Acesso

Open Access