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Chapter 8 Non-thermal Plasma Technology for the Improvement of Scaffolds for Tissue Engineering and Regenerative Medicine - A Review

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Non-thermal plasma technology is one of those techniques that suffer relatively little from diffusion limits, slow kinetics, and complex geometries compared to more traditional liquid-based chemical surface modification techniques. Combined with a lack of solvents, preservation of the bulk propertie...

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Bibliographic Details
Main Author: Morent, Rino (auth)
Other Authors: Ghobeira, Rouba (auth), Cools, Pieter (auth), van Geyterand, Nathalie (auth), van Vrekhem, Stijn (auth), Van Vrekhem, Stijn (auth), De Geyterand, Nathalie (auth)
Format: Electronic Book Chapter
Language:English
Published: InTechOpen 2016
Subjects:
Science: general issues
non-thermal plasma technology
tissue engineering
scaffold fabrication
biomaterials
Blood plasma
Collagen
Electrospinning
Osteoblast
Polylactic acid
Online Access:OAPEN Library: download the publication
OAPEN Library: description of the publication
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Summary:Non-thermal plasma technology is one of those techniques that suffer relatively little from diffusion limits, slow kinetics, and complex geometries compared to more traditional liquid-based chemical surface modification techniques. Combined with a lack of solvents, preservation of the bulk properties, and fast treatment times; it is a well-liked technique for the treatment of materials for biomedical applications. In this book chapter, a review will be given on what the scientific community determined to be essential to obtain appropriate scaffolds for tissue engineering and how plasma scientists have used non-thermal plasma technology to accomplish this. A distinction will be made depending on the scaffold fabrication technique, as each technique has its own set of specific problems that need to be tackled. Fabrication techniques will include traditional fabrication methods, rapid prototyping, and electrospinning. As for the different plasma techniques, both plasma activation and grafting/polymerization will be included in the review and linked to the in-vitro/in-vivo response to these treatments. The literature review itself is preceded by a more general overview on cell communication, giving useful insights on how surface modification strategies should be developed.
ISBN:62007
Access:Open Access

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