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The Pangenome Diversity, Dynamics and Evolution of Genomes

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This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology...

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Bibliographic Details
Other Authors: Tettelin, Hervé (Editor), Medini, Duccio (Editor)
Format: Electronic Book Chapter
Language:English
Published: Cham Springer Nature 2020
Subjects:
Microbiology (non-medical)
Evolution
Applied mathematics
Ecological science, the Biosphere
Medical genetics
Genetics (non-medical)
Microbial Genetics and Genomics
Evolutionary Biology
Genetics and Population Dynamics
Microbial Ecology
Human Genetics
Genetics and Genomics
Comparative genomics
Metagenomics
Microbial Population Analysis
Pangenome Profile
Supra-Genome Analysis
Adaptive Evolution
Computational Tools
Bioinformatic Genomics
Core Dispensable Genome
Selection, Recombination, Composition
Acquired Resistance
Bacterial Species Concept
Genomic Diversity
Bacterial Ecology, Microevolution
Open Access
Pan-metagenomics
Pan-microbiomics
Pan-epigenome
Gene Transfer
Pan-phenomes
Online Access:OAPEN Library: download the publication
OAPEN Library: description of the publication
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Summary:This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species challenges existing views and has profound consequences for our understanding of the fundamental mechanisms underpinning bacterial biology and evolution. The underlying rationale extends well beyond the initial prokaryotic focus to all kingdoms of life and evolves into similar concepts for metagenomes, phenomes and epigenomes. The book's respective chapters address a range of topics, from the serendipitous emergence of the pan-genome concept and its impacts on the fields of microbiology, vaccinology and antimicrobial resistance, to the study of microbial communities, bioinformatic applications and mathematical models that tie in with complex systems and economic theory. Given its scope, the book will appeal to a broad readership interested in population dynamics, evolutionary biology and genomics.
Physical Description:1 electronic resource (307 p.)
ISBN:978-3-030-38281-0
Access:Open Access

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