Mathematical Modeling of the Human Brain From Magnetic Resonance Images to Finite Element Simulation

This open access book bridges common tools in medical imaging and neuroscience with the numerical solution of brain modelling PDEs. The connection between these areas is established through the use of two existing tools, FreeSurfer and FEniCS, and one novel tool, the SVM-Tk, developed for this book....

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Bibliographic Details
Main Author: Mardal, Kent-André (auth)
Other Authors: Rognes, Marie E. (auth), Thompson, Travis B. (auth), Valnes, Lars Magnus (auth)
Format: Electronic Book Chapter
Language:English
Published: Cham Springer Nature 2022
Series:Simula SpringerBriefs on Computing 10
Subjects:
Online Access:OAPEN Library: download the publication
OAPEN Library: description of the publication
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520 |a This open access book bridges common tools in medical imaging and neuroscience with the numerical solution of brain modelling PDEs. The connection between these areas is established through the use of two existing tools, FreeSurfer and FEniCS, and one novel tool, the SVM-Tk, developed for this book. The reader will learn the basics of magnetic resonance imaging and quickly proceed to generating their first FEniCS brain meshes from T1-weighted images. The book's presentation concludes with the reader solving a simplified PDE model of gadobutrol diffusion in the brain that incorporates diffusion tensor images, of various resolution, and complex, multi-domain, variable-resolution FEniCS meshes with detailed markings of anatomical brain regions. After completing this book, the reader will have a solid foundation for performing patient-specific finite element simulations of biomechanical models of the human brain. 
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