Cerebral Small Vessel Disease and Cerebral Amyloid Angiopathy Neuroimaging markers, cognitive features and rehabilitative issues
Sporadic cerebral small vessel disease (SVD) is considered to be among the most commonly known neuropathological processes in the brain, hosting a crucial role in stroke, cognitive impairment, and functional loss in elderly subjects. We investigated clinical (neuroimaging and cognitive) biomarkers i...
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| Autor principal: | |
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| Formato: | Recurso Eletrônico Capítulo de Livro |
| Idioma: | inglês |
| Publicado em: |
Florence
Firenze University Press
2018
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| coleção: | Premio Tesi di Dottorato
67 |
| Assuntos: | |
| Acesso em linha: | OAPEN Library: download the publication OAPEN Library: description of the publication |
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| Resumo: | Sporadic cerebral small vessel disease (SVD) is considered to be among the most commonly known neuropathological processes in the brain, hosting a crucial role in stroke, cognitive impairment, and functional loss in elderly subjects. We investigated clinical (neuroimaging and cognitive) biomarkers in the SVD, through a series of analyses from our five studies. Sporadic cerebral SVD is a complex 'micro-world' to be globally considered. All the relevant lesion types and SVD neuroimaging burden should be taken into account. The cumulative effects of microangiopathy burden in the brain of patients affected by SVD are crucial. Cognitive rehabilitation could represent a promising approach to prevent vascular dementia or to improve cognitive performances in patients with cerebral SVD. Longitudinal studies may provide more robust information about the progression and prognostic significance of our findings. |
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| Descrição Física: | 1 electronic resource (182 p.) |
| ISBN: | 978-88-6453-779-5 9788864537795 9788864537788 9788892730861 |
| Acesso: | Open Access |