RNA, the Epicenter of Genetic Information

The origin story and emergence of molecular biology is muddled. The early triumphs in bacterial genetics and the complexity of animal and plant genomes complicate an intricate history. This book documents the many advances, as well as the prejudices and founder fallacies. It highlights the premature...

Szczegółowa specyfikacja

Zapisane w:
Opis bibliograficzny
1. autor: Mattick, John (auth)
Kolejni autorzy: Amaral, Paulo (auth)
Format: Elektroniczne Rozdział
Język:angielski
Wydane: Taylor & Francis 2023
Hasła przedmiotowe:
Dostęp online:OAPEN Library: download the publication
OAPEN Library: description of the publication
Etykiety: Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!

MARC

LEADER 00000naaaa2200000uu 4500
001 oapen_2024_20_500_12657_57585
005 20220722
003 oapen
006 m o d
007 cr|mn|---annan
008 20220722s2023 xx |||||o ||| 0|eng d
020 |a 9781003109242 
020 |a 9781000623086 
020 |a 9781003109242 
020 |a 9780367623920 
020 |a 9780367567781 
040 |a oapen  |c oapen 
024 7 |a 10.1201/9781003109242  |c doi 
041 0 |a eng 
042 |a dc 
072 7 |a PSD  |2 bicssc 
072 7 |a PSF  |2 bicssc 
072 7 |a PSAK  |2 bicssc 
072 7 |a PSG  |2 bicssc 
072 7 |a PSB  |2 bicssc 
072 7 |a PNN  |2 bicssc 
072 7 |a TCB  |2 bicssc 
072 7 |a PS  |2 bicssc 
072 7 |a PHVN  |2 bicssc 
100 1 |a Mattick, John  |4 auth 
700 1 |a Amaral, Paulo  |4 auth 
245 1 0 |a RNA, the Epicenter of Genetic Information 
260 |b Taylor & Francis  |c 2023 
300 |a 1 electronic resource (400 p.) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
506 0 |a Open Access  |2 star  |f Unrestricted online access 
520 |a The origin story and emergence of molecular biology is muddled. The early triumphs in bacterial genetics and the complexity of animal and plant genomes complicate an intricate history. This book documents the many advances, as well as the prejudices and founder fallacies. It highlights the premature relegation of RNA to simply an intermediate between gene and protein, the underestimation of the amount of information required to program the development of multicellular organisms, and the dawning realization that RNA is the cornerstone of cell biology, development, brain function and probably evolution itself. Key personalities, their hubris as well as prescient predictions are richly illustrated with quotes, archival material, photographs, diagrams and references to bring the people, ideas and discoveries to life, from the conceptual cradles of molecular biology to the current revolution in the understanding of genetic information. Key Features Documents the confused early history of DNA, RNA and proteins - a transformative history of molecular biology like no other. Integrates the influences of biochemistry and genetics on the landscape of molecular biology. Chronicles the important discoveries, preconceptions and misconceptions that retarded or misdirected progress. Highlights major pioneers and contributors to molecular biology, with a focus on RNA and noncoding DNA. Summarizes the mounting evidence for the central roles of non-protein-coding RNA in cell and developmental biology. Provides a thought-provoking retrospective and forward-looking perspective for advanced students and professional researchers. 
540 |a Creative Commons  |f by-nc-nd/4.0  |2 cc  |4 http://creativecommons.org/licenses/by-nc-nd/4.0 
546 |a English 
650 7 |a Molecular biology  |2 bicssc 
650 7 |a Cellular biology (cytology)  |2 bicssc 
650 7 |a Genetics (non-medical)  |2 bicssc 
650 7 |a Microbiology (non-medical)  |2 bicssc 
650 7 |a Biochemistry  |2 bicssc 
650 7 |a Organic chemistry  |2 bicssc 
650 7 |a Biotechnology  |2 bicssc 
650 7 |a Biology, life sciences  |2 bicssc 
650 7 |a Biophysics  |2 bicssc 
653 |a Cloning 
653 |a Double Helix 
653 |a Genetic Code 
653 |a Genetic Engineering 
653 |a Gene Regulation 
653 |a Genome Structure and Function 
856 4 0 |a www.oapen.org  |u https://library.oapen.org/bitstream/id/db4d22aa-4fee-47c0-9780-e9955600db29/9781000623086.pdf  |7 0  |z OAPEN Library: download the publication 
856 4 0 |a www.oapen.org  |u https://library.oapen.org/handle/20.500.12657/57585  |7 0  |z OAPEN Library: description of the publication