Glaucoma: May new technologies help in early diagnosis?

• Main Authors: Casillo L (Author), Tricarico S (Author), Vingolo EM (Author)
• Format: Book
• Published: Journal of Clinical Research and Ophthalmology - Peertechz Publications, 2018-03-16.
• Subjects: Research Article
• Online Access: Connect to this object online.

<p><strong>Purpose: </strong>to identify new functional parameters that may help in the early primary open angle</p><p>glaucoma (POAG) diagnosis. Materials and <br></p><p><strong>Methods:</strong> 40 subjects were enrolled: 20 healthy subjects and 20 POAG patients, all aged between 30 and 65 years, for a total of 79 eyes, including 40 healthy and 39 POAG. All subjects underwent microperimetric test, Nidek MP-1 (NAVIS, software version 1.7.6; Nidek Technologies, Japan) using Humphrey 10-2 pattern with manual polygonize of upper and lower hemifi elds. Mean hemifi eld sensitivity was evaluated. <br></p><p><strong>Results: </strong>Analysis reported signifi cant differences of mean retinal sensitivity of the upper hemifi elds between POAG and healthy subjects (p < 0.025), thus highly signifi cant. Equally signifi cant (p < 0.025) was the comparison of ratio (upper / lower hemifi eld) between the two groups. There was not statistically signifi cant difference of sensitivity of lower hemifi elds (p> 0.05).</p><p><strong>Conclusion: </strong>signifi cant difference was observed between healthy and POAG groups using Humphrey 10-2 vertical asymmetry index. Therefore, it appears to be an unprecedented microperimetric diagnostic tool.</p>