Fresh frozen plasma as a source of plasminogen for ligneous conjunctivitis: Case report and a review of the literature
<p>Purpose: To describe management of a patient with ligneous conjunctivitis secondary to plasminogen deficiency and review the literature on treatment with plasminogen.</p><p>Design: Interventional case report.</p><p>Methods: A 6-year-old Caucasian girl developed ligne...
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| Main Authors: | , , , , , |
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| Format: | Book |
| Published: |
Journal of Clinical Research and Ophthalmology - Peertechz Publications,
2021-07-19.
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| Summary: | <p>Purpose: To describe management of a patient with ligneous conjunctivitis secondary to plasminogen deficiency and review the literature on treatment with plasminogen.</p><p>Design: Interventional case report.</p><p>Methods: A 6-year-old Caucasian girl developed ligneous conjunctivitis recalcitrant to debridement and treatment with topical cyclosporin A and steroids. The literature was reviewed regarding treatment of ligneous conjunctivitis with plasminogen.</p><p>Results: The patient was treated with plasminogen containing drops derived from her father's fresh frozen plasma. The ligneous conjunctivitis resolved, and the patient was managed on these drops for the following 8 years, initiating treatment for flares and tapering according to clinical response.</p><p>Conclusions: Plasminogen drops concentrated from fresh frozen plasma are a safe and effective option for long-term treatment of ligneous conjunctivitis.</p> |
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| DOI: | 10.17352/2455-1414.000090 |