Evaluation of the efficacy of the utilization of the imipramine for patients with allergic rhinitis
<p><strong>Background:</strong> allergic rhinitis is an infl ammatory process of the upper respiratory tract with a continuous symptom that last for hour or more with symptom affect patient's work and quality of life. </p><p><strong>Methodology:</strong>...
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| Váldodahkkit: | , , , , |
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| Materiálatiipa: | Girji |
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Archives of Otolaryngology and Rhinology - Peertechz Publications,
2017-07-26.
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| Čoahkkáigeassu: | <p><strong>Background:</strong> allergic rhinitis is an infl ammatory process of the upper respiratory tract with a continuous symptom that last for hour or more with symptom affect patient's work and quality of life. </p><p><strong>Methodology:</strong> a randomized controlled trial in which we enrolled 284 patients with allergic rhinitis for periods longer than 4 days/week and for more than 4 consecutive weeks divided into two groups. Group A (n=142) received Imipramine 75 mg/day for 90 days .Group B (n=142), the control group, received desloratadine 5 mg / day for 90 days.</p><p><strong>Results:</strong> The mean visual analogue score nasal symptoms intensity (sneezing, Nasal obstruction, watery rhinorrhea and itchy nose) showed a statistically signifi cantly improvement in group A (treated with Imipramine) compared with group B (treated with desloratadine) after the same treatment period.</p><p><strong>Conclusion:</strong> Imipramine could be used in treatment patients with allergic rhinitis as it is effective as an antihistaminic besides its main action in reliving psychosocial stresses.</p> |
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| DOI: | 10.17352/2455-1759.000052 |