Diffusion-weighted magnetic resonance imaging with echo-planar and non-echo-planar (PROPELLER) techniques in the clinical evaluation of cholesteatoma
<p>Background: Diffusion-weighted magnetic resonance imaging (DWI) is an alternative to second-look surgery for the detection of cholesteatoma.</p><p>Purpose: To assess the utility of DWI with echo-planar (EPI-DWI) and non-echo-planar (PROPELLER) sequences for the diagnosis of prim...
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Archives of Otolaryngology and Rhinology - Peertechz Publications,
2019-02-11.
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LEADER | 00000 am a22000003u 4500 | ||
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001 | peertech__10_17352_2455-1759_000089 | ||
042 | |a dc | ||
100 | 1 | 0 | |a María Dolores Moreno-Ramos |e author |
700 | 1 | 0 | |a Miguel Olivencia Pérez |e author |
700 | 1 | 0 | |a Juan Antonio Ibáñez Rodríguez |e author |
700 | 1 | 0 | |a Mª José Gómez Galán |e author |
700 | 1 | 0 | |a Francisco Javier Ramos Medrano |e author |
245 | 0 | 0 | |a Diffusion-weighted magnetic resonance imaging with echo-planar and non-echo-planar (PROPELLER) techniques in the clinical evaluation of cholesteatoma |
260 | |b Archives of Otolaryngology and Rhinology - Peertechz Publications, |c 2019-02-11. | ||
520 | |a <p>Background: Diffusion-weighted magnetic resonance imaging (DWI) is an alternative to second-look surgery for the detection of cholesteatoma.</p><p>Purpose: To assess the utility of DWI with echo-planar (EPI-DWI) and non-echo-planar (PROPELLER) sequences for the diagnosis of primary and recurrent cholesteatoma. </p><p>Materials and methods: A prospective study of 33 ears, 21 with previous cholesteatoma surgery. Twelve patients were asymptomatic, with 4 showing signs suggestive of cholesteatoma in previous CT scans. The MRI protocol was: axial and coronal T1-weighted and T2-weighted imaging, and diffusion-weighted sequences by both EPI-DWI and PROPELLER techniques. The results were correlated with the clinical examination and subsequent surgical findings. Ten patients undergoing ear surgery for other reasons were included as negative controls.</p><p>Results: The diagnostic accuracy was calculated with the 22 patients who underwent surgery and the negative controls. Both diffusion-weighted sequences showed a specificity of 100%. The sensitivity of PROPELLER was 95%, compared to 20% for EPI-DWI. The latter showed non-specific imaging with bone artefacts, thus making impossible to confirm or exclude the diagnosis. The PROPELLER technique yielded one false negative, compared with 16 by EPI-DWI. Both techniques gave a false negative in one case of a primary cholesteatoma. A positive result was obtained in two patients with no clinical suspicion of recurrence. </p><p>Conclusions: In contrast to EPI-DWI, PROPELLER is a reliable technique for diagnosing cholesteatoma. As positive results were found in asymptomatic patients, we recommend regular monitoring by PROPELLER, even in the absence of clinical findings.</p> | ||
540 | |a Copyright © María Dolores Moreno-Ramos et al. | ||
546 | |a en | ||
655 | 7 | |a Research Article |2 local | |
856 | 4 | 1 | |u https://doi.org/10.17352/2455-1759.000089 |z Connect to this object online. |