Comparative Study of Glyceryl Trinitrate Ointment versus Lateral Internal Sphincterotomy in Management of Chronic Anal Fissure
<p><strong>Aims and Objectives: </strong>To prospectively evaluate and compare effectiveness of topical 0.2% glyceryl trinitrate ointment vs lateral internal sphincterotomy in treatment of patients with chronic anal fissure. <strong>Material and Methods: </strong>The st...
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Archives of Clinical Gastroenterology - Peertechz Publications,
2016-04-30.
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LEADER | 00000 am a22000003u 4500 | ||
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001 | peertech__10_17352_2455-2283_000013 | ||
042 | |a dc | ||
100 | 1 | 0 | |a AR Bansal |e author |
700 | 1 | 0 | |a Rathindra Tripura |e author |
700 | 1 | 0 | |a Rajesh Godara |e author |
700 | 1 | 0 | |a Jaikaran |e author |
245 | 0 | 0 | |a Comparative Study of Glyceryl Trinitrate Ointment versus Lateral Internal Sphincterotomy in Management of Chronic Anal Fissure |
260 | |b Archives of Clinical Gastroenterology - Peertechz Publications, |c 2016-04-30. | ||
520 | |a <p><strong>Aims and Objectives: </strong>To prospectively evaluate and compare effectiveness of topical 0.2% glyceryl trinitrate ointment vs lateral internal sphincterotomy in treatment of patients with chronic anal fissure. <strong>Material and Methods: </strong>The study included a total of 50 patients presented with chronic anal fissure, divided into two groups by computer generated randomization. Group A included 25 patients with chronic anal fissure treated with local glyceryl trinitrate ointment 0.2% whereas Group B included 25 patients managed by lateral internal sphincterotomy.</p><p><strong>Results: </strong>The mean age of patients in group A was 34.6±12.8 years and in Group B was 32.12±11.57 years (p>.05). In group A, out of 25 patients, 19 were male and 6 females, whereas in group B, there were 20 males and 5 females. The mean pain score of patients before treatment in group A was 8.64±0.95 where as in group B was 8.44±1.19. At the end of six weeks of treatment the mean pain score was 1.64±2.43 in group A and 0.24±1.20 in group B respectively. Complete healing was observed in 18 out of 25 (72%) patients in group A whereas all 25 (100%) patients in group B had completely healed fissures at the end of six weeks. Except headache which was reported in 9 out of 25 (36%) patients in group A no other side effect was seen in this group. Whereas only 1 out of 25(4%) patients in group B developed haematoma in the perianal area, which was relieved conservatively within 1 week. <br></p><p><strong>Conclusion: </strong>Glyceryl trinitrate ointment is a good alternative mode of therapy, hence lateral internal sphincterotomy may be reserved for patients who fail to respond to initial glyceryl trinitrate therapy.</p> | ||
540 | |a Copyright © AR Bansal et al. | ||
546 | |a en | ||
655 | 7 | |a Research Article |2 local | |
856 | 4 | 1 | |u https://doi.org/10.17352/2455-2283.000013 |z Connect to this object online. |