Gastrointestinal Amyloidosis: An Unusual Case Where Protein-Losing Enteropathy is Associated to Malabsorption
<p><strong>Introduction: </strong>The systemic amyloidosis usually doesn't save the digestive tract, but this involvement is present in approximately 60% of patients with AA Amyloidosis and only in 8% and 1% of patients with AL Amyloidosis (respectively through biopsy and clin...
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| Main Authors: | , |
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| Format: | Book |
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Archives of Clinical Gastroenterology - Peertechz Publications,
2016-06-25.
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| Online Access: | Connect to this object online. |
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| Summary: | <p><strong>Introduction: </strong>The systemic amyloidosis usually doesn't save the digestive tract, but this involvement is present in approximately 60% of patients with AA Amyloidosis and only in 8% and 1% of patients with AL Amyloidosis (respectively through biopsy and clinically). Beside gastrointestinal involvement is rarely symptomatic and clinical events are not specific. Enteropathy protein-losing is a rare condition caused by excessive loss of serum protein in the gastrointestinal tract, resulting in hypoproteinaemia, edema, and, sometimes, pleural/pericardial effusions. The diagnosis should be taken into account only when other causes have been excluded. Gastrointestinal AL amyloidosis usually appears with constipation and mechanical obstruction/ pseudobstruction, on the contrary enteropathy protein-losing and malabsorption are rare. <br></p><p><strong>Case report: </strong>We report the case of a 59-year -old patient, with AL amyloidosis, who suffered from weight loss and ascites effusion related to an AL amyloidosis. </p><p><strong>Discussion: </strong>The case is unusual, both because of the extension in the gastrointestinal tract and for its unusual clinical presentation as enteropathy protein-losing associated with malabsorption.</p> |
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| DOI: | 10.17352/2455-2283.000020 |