Randomized Vitamin D Supplementation in Vitamin D Deficient Obese Children from West Virginia

• Автори: Yoram Elitsur (Автор), Deborah L Preston (Автор)
• Формат: Книга
• Опубліковано: Archives of Clinical Gastroenterology - Peertechz Publications, 2016-12-08.
• Предмети: Research Article
• Онлайн доступ: Connect to this object online.

Резюме

<p><strong>Objective:</strong> Vitamin D (Vit D) defi ciency is a very common problem in obese children, but clinical guidelines for maintenance or treatment have not been published for this population. The aim was to assess the benefi t of 2 months Vit D supplementation given to defi cient obese children from WV. <br></p><p><strong>Design: </strong>Vit D defi cient obese children were prospectively recruited. Exclusion criteria included <8 years, and medical conditions that may affect Vit D homeostasis. Participants were randomized into two  <strong>supplement groups: </strong>5,000IU/day (Group A) or 50,000IU/week (Group B). Serum 25(OH)D levels were measured at baseline and post-treatment. <br></p><p><strong>Results: </strong>Sixty obese children were screened of whom 39 (65%) were defi cient (<20ng/ml). Of the 39  recruited, 26 completed the study. The mean serum 25(OH)D after 2 months treatment were signifi cantly <br></p><p>higher in Group B (p= 0.02), but most reached normal levels (>30ng/ml). </p><p><strong>Conclusions: </strong>Two months Vit D supplementation (5000IU/day or 50,000IU/week) was suffi cient to normalize 25(OH)D levels in Vit D defi cient obese West Virginian children.</p>

DOI

10.17352/2455-2283.000024