Randomized Vitamin D Supplementation in Vitamin D Deficient Obese Children from West Virginia
<p><strong>Objective:</strong> Vitamin D (Vit D) defi ciency is a very common problem in obese children, but clinical guidelines for maintenance or treatment have not been published for this population. The aim was to assess the benefi t of 2 months Vit D supplementation given to d...
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| Main Authors: | , |
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| Format: | Book |
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Archives of Clinical Gastroenterology - Peertechz Publications,
2016-12-08.
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| Online Access: | Connect to this object online. |
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| Summary: | <p><strong>Objective:</strong> Vitamin D (Vit D) defi ciency is a very common problem in obese children, but clinical guidelines for maintenance or treatment have not been published for this population. The aim was to assess the benefi t of 2 months Vit D supplementation given to defi cient obese children from WV. <br></p><p><strong>Design: </strong>Vit D defi cient obese children were prospectively recruited. Exclusion criteria included <8 years, and medical conditions that may affect Vit D homeostasis. Participants were randomized into two <strong>supplement groups: </strong>5,000IU/day (Group A) or 50,000IU/week (Group B). Serum 25(OH)D levels were measured at baseline and post-treatment. <br></p><p><strong>Results: </strong>Sixty obese children were screened of whom 39 (65%) were defi cient (<20ng/ml). Of the 39 recruited, 26 completed the study. The mean serum 25(OH)D after 2 months treatment were signifi cantly <br></p><p>higher in Group B (p= 0.02), but most reached normal levels (>30ng/ml). </p><p><strong>Conclusions: </strong>Two months Vit D supplementation (5000IU/day or 50,000IU/week) was suffi cient to normalize 25(OH)D levels in Vit D defi cient obese West Virginian children.</p> |
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| DOI: | 10.17352/2455-2283.000024 |