Gastrointestinally mediated food allergy causing Spondyloarthritis-like disease
<p>Gastrointestinally-mediated food allergy (GMA) incidentally may cause non-erosive oligoarthritis.</p><p>A 56-year-old woman with seronegative spondyloarthritis observed arthritic flares following ingestion of certain foods. Blood analyses were unremarkable. Segmental gut lavage...
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| Main Authors: | , , , , |
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| Format: | Book |
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Archives of Clinical Gastroenterology - Peertechz Publications,
2020-07-15.
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| Online Access: | Connect to this object online. |
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| Summary: | <p>Gastrointestinally-mediated food allergy (GMA) incidentally may cause non-erosive oligoarthritis.</p><p>A 56-year-old woman with seronegative spondyloarthritis observed arthritic flares following ingestion of certain foods. Blood analyses were unremarkable. Segmental gut lavage revealed plasmacellular infiltrates and eosinophilia in terminal ileum. Food allergen-specific IgE-analysis of lavage fluid showed significant polyvalent intestinal IgE-sensitization (>0.35kU/mg protein) towards wheat, rye, egg, soybean, pork, beef, nuts. Repeated exposure to the aforementioned foods caused arthritis within 48 hours; elimination diet engendered long-term remission. Seronegative local IgE-mediated GMA (type I) was diagnosed.</p><p>Especially seronegative rheumatoid arthritis and undifferentiated oligoarthritis should be scrutinized for food-related muscoloskeletal symptoms before initiating immunosuppression. </p> |
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| DOI: | 10.17352/2455-2283.000078 |