Tetrahydrobiopterin Concentrations in Normal and Coronary Artery Diseased Heart Tissue

• Main Authors: Erland Arning (Author), Brian D Lowes (Author), Matthew RG Taylor (Author), Xingli Meng (Author), Raphael Schiffmann (Author), Teodoro Bottiglieri (Author)
• Format: Book
• Published: Journal of Cardiovascular Medicine and Cardiology - Peertechz Publications, 2016-05-06.
• Subjects: Research Article
• Online Access: Connect to this object online.

<p>Tetrahydrobiopterin (BH4) is an essential cofactor that controls the enzymatic activity of aromatic amino acid hydroxylases as well as all forms of nitric oxide synthase (NOS), which include endothelial (eNOS), neuronal (nNOS) and inducible (iNOS) isoforms [1]. In coronary arteries, reduced...