Infective Endocardatis at the Yaounde General Hospital: Clinical aspects and outcome (Case Series)

• Main Authors: Jérôme Boombhi (Author), Alain Menanga (Author), Bâ Hamadou (Author), André- Michel Yomba (Author), Samuel Kingue (Author)
• Format: Book
• Published: Journal of Cardiovascular Medicine and Cardiology - Peertechz Publications, 2017-08-16.
• Subjects: Research Article
• Online Access: Connect to this object online.

<p><strong>Introduction: </strong>Infectious endocarditis (IE) is a severe pathology. Its epidemiological, clinical and evolutive profi le varies a lot depending if it is in the context of a developed country or developing country. In our context, very little data exists on the subject.</p><p><strong>Objectives:</strong> Describe the clinical aspects and outcome of IE in the Yaoundé general hospital. <strong><br></strong></p><p><strong>Methods: </strong>We carried out a descriptive retrospective study using clinical records of patients who had presented with IE in the cardiology unit of the Yaoundé general hospital from June of 2008 to May of 2013.</p><p><strong>Results: </strong>During this 5year period, 1846 patients were admitted in the cardiology unit and 10 of these cases were IE giving a hospital prevalence of 0.54%. The sex ratio was 1. The average age of the patients was 44.7 +/- 14.2 years. Rhumatismal valvulopathy was found as the most frequent predisposing factor, with 50% of the cases. The most frequent symptoms were fever and a heart murmur, which were found in 100% and 90% of the cases respectively. An infl ammatory syndrome with anaemia was found in 90% of cases, leucocytosis with predominance of polymorphological neutrophils (PMN) in 80%, a raised ESR and CRP in all the patients. Hemocultures were positive only in 30% of the cases; however 60% of the patients had just one pair hemoculture done. Streptococcus was found in 2 cases and staphylococcus in 1 case. On echocardiography, vegetation and valvular regurgitation were found in all the patients. The antibiotherapy protocols were globally in conformity with recommendations and 40% of the patients completed their treatment. We found 4 deaths.</p><p><strong>Conclusion:</strong> IE is a rare pathology in our unit. Rhumatismal valvulopathy is the principal predisposing factor. Its management is limited by technical conditions and economic difficulties.</p>