An Updated Systematic Review and Meta-analysis of the Short- and Long-term Outcomes of Percutaneous Coronary Intervention for Patients with Severe Left Ventricular Systolic Dysfunction

• Main Authors: Nuremanguli Abudukeremu§ (Author), Zi- Xiang Yu1§ (Author), Yi-Ning Yang (Author), Siew- Pang Chan (Author), Xiao-Mei Li (Author), Fen Liu (Author), Yi-Tong Ma (Author)
• Format: Book
• Published: Journal of Cardiovascular Medicine and Cardiology - Peertechz Publications, 2018-11-06.
• Subjects: Research Article
• Online Access: Connect to this object online.

<p><strong>Background</strong>: Coronary artery disease (CAD) is the most common cause of left ventricular dysfunction</p><p>(LVD). Confl icting evidence exists with regards to available treatments and patient prognosis.</p><p>Revascularization may improve ventricular function while coronary artery bypass surgery (CABG) has</p><p>signifi cantly improved survival. The effectiveness of percutaneous coronary intervention (PCI) has also</p><p>not been thoroughly investigated to date.</p><p><strong>Objectives</strong>: To ascertain the in-hospital and long-term (≥1 year) outcomes of CAD patients with LV</p><p>systolic dysfunction (ejection fraction ≤40%) after PCI according to a meta-analysis.</p><p><strong>Methods</strong>: A systematic literature search and a series of random-effect meta-analyses were conducted to evaluate the short- and long-term outcomes of PCI of the selected studies. Single-center studies andthose that did not report evidence on long-term mortality were excluded in the analysis. All statistical tests were performed with 95% confi dence intervals. A p-value of less than 0.05 was considered statistically significant.</p>