Severe Repeated Hypotension Occurred after Rocuronium Administrations in a Morbidly Obese Patient: A Case Report

<p>Rocuronium has the most rapid onset of action among the nondepolarizing neuromuscular blocking drugs; doses of 0.6-0.9 mg/ Kg guarantee a complete block in about 60-90 seconds and good or excellent intubating conditions in 60 seconds [1,2].</p><p>Its pharmacokinetics and pharmac...

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Autores principales: Fabio Silvio Mario Araimo Morselli (Autor), Paolo Tordiglione (Autor), Ilaria Scarpa (Autor), Francesco Zuccarini (Autor), Giovanni Rosa (Autor)
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Publicado: Global Journal of Anesthesiology - Peertechz Publications, 2014-09-06.
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042 |a dc 
100 1 0 |a Fabio Silvio Mario Araimo Morselli  |e author 
700 1 0 |a  Paolo Tordiglione  |e author 
700 1 0 |a  Ilaria Scarpa  |e author 
700 1 0 |a  Francesco Zuccarini  |e author 
700 1 0 |a  Giovanni Rosa  |e author 
245 0 0 |a Severe Repeated Hypotension Occurred after Rocuronium Administrations in a Morbidly Obese Patient: A Case Report 
260 |b Global Journal of Anesthesiology - Peertechz Publications,   |c 2014-09-06. 
520 |a <p>Rocuronium has the most rapid onset of action among the nondepolarizing neuromuscular blocking drugs; doses of 0.6-0.9 mg/ Kg guarantee a complete block in about 60-90 seconds and good or excellent intubating conditions in 60 seconds [1,2].</p><p>Its pharmacokinetics and pharmacodynamics can be influenced by different factors as age, inhaled anesthetics, hepatic and renal insufficiency, hypothermia, gender and obesity [3-8].</p><p>Rocuronium has been shown to cause less histamine release and cardiovascular instability than benzylisoquinolinum neuromuscular blocking agents such as atracurium and mivacurium [9], however it can act as an antigen: in our clinical experience three acute reactions occurred after its administration in the same patient.</p> 
540 |a Copyright © Fabio Silvio Mario Araimo Morselli et al. 
546 |a en 
655 7 |a Case Report  |2 local 
856 4 1 |u https://doi.org/10.17352/2455-3476.000003  |z Connect to this object online.