Comparison of dexamethasone, granisetron and haloperidol in prevention of postoperative nausea and vomiting following laparoscopic surgeries: A prospective, double-blinded study
<p>Background: Laparoscopic surgeries are most commonly performed surgeries. However, they are associated with increased incidences of postoperative nausea and vomiting. </p><p>Aim: We aimed to compare the effectiveness of dexamethasone, haloperidol, granisetron in prevention of po...
Saved in:
Main Authors: | , , |
---|---|
Format: | Book |
Published: |
Global Journal of Anesthesiology - Peertechz Publications,
2019-03-29.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
MARC
LEADER | 00000 am a22000003u 4500 | ||
---|---|---|---|
001 | peertech__10_17352_2455-3476_000045 | ||
042 | |a dc | ||
100 | 1 | 0 | |a Shikha Sharma |e author |
700 | 1 | 0 | |a Gnanasekar N |e author |
700 | 1 | 0 | |a Pranjali Kurhekar |e author |
245 | 0 | 0 | |a Comparison of dexamethasone, granisetron and haloperidol in prevention of postoperative nausea and vomiting following laparoscopic surgeries: A prospective, double-blinded study |
260 | |b Global Journal of Anesthesiology - Peertechz Publications, |c 2019-03-29. | ||
520 | |a <p>Background: Laparoscopic surgeries are most commonly performed surgeries. However, they are associated with increased incidences of postoperative nausea and vomiting. </p><p>Aim: We aimed to compare the effectiveness of dexamethasone, haloperidol, granisetron in prevention of postoperative nausea and vomiting following laparoscopic surgeries. </p><p>Methods: We conducted a randomized, double-blinded study including 90 patients both males and females undergoing laparoscopic surgeries in a tertiary hospital over 18 months. The subjects were randomized into three groups. Group I Dexamethasone 8mg, Group II Granisetron 2mg, Group III Haloperidol 1mg (n=30 each group). The study drugs were administered intravenously immediately after intubation. Patients were observed every 4th hourly till 24 hours for incidence of nausea, vomiting, pain and sedation. </p><p>Results: Incidence of vomiting was significantly less in dexamethasone group (p=0.047) as compared to granisetron and haloperidol and was statistically significant (p<0.047).There was no significant difference in the incidence of vomiting between other two groups. All other parameters were comparable in all the groups. </p><p>Conclusion: Dexamethasone in the dose of 8mg significantly reduces incidence of vomiting in laparoscopic surgeries than haloperidol and granisetron. </p><p>Trial Registry: Clinical Trial Registry of India 2018/03/018324</p> | ||
540 | |a Copyright © Shikha Sharma et al. | ||
546 | |a en | ||
655 | 7 | |a Research Article |2 local | |
856 | 4 | 1 | |u https://doi.org/10.17352/2455-3476.000045 |z Connect to this object online. |