Research progress of near-infrared fl uorescence immunoassay
<p>Near-infrared fl uorescence immunoassay has been widely studied in the bio analytical fi eld. This</p><p>review mainly introduces the basic principles of near-infrared spectroscopy and near-infrared detection</p><p>technology, and summarizes the properties, character...
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| Main Authors: | , , , , , , , , |
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| Format: | Book |
| Published: |
International Journal of Nanomaterials, Nanotechnology and Nanomedicine - Peertechz Publications,
2019-02-27.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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| Summary: | <p>Near-infrared fl uorescence immunoassay has been widely studied in the bio analytical fi eld. This</p><p>review mainly introduces the basic principles of near-infrared spectroscopy and near-infrared detection</p><p>technology, and summarizes the properties, characteristics and recent improvement of optical properties</p><p>and signal intensity of three near-infrared fl uorescence probes (i.e. organic fl uorophores, quantum dots</p><p>and rare earth compounds). We describe the applications of near-infrared fl uorescence technology in</p><p>immunoassay, and prospect the application potential of lateral fl ow assay (LFA) based on this probe in</p><p>the rapid detection of pathogens. Our team intends to establish a new platform which has highly sensitive</p><p>near-infrared fl uorescence probes (NIFPs) combined with portable and simple immunochromatographic</p><p>test strips (ICTSs) for rapid detection of food borne viruses. This will provide technical support for a rapid</p><p>detection on the port.</p><p>Practical applications</p><p>The applications of near-infrared fl uorescence probes (NIFPs) in immunological analysis and clinically</p><p>important biomarkers were also elaborated. Moreover, NIFPs-based immunoassay adaptable for rapid</p><p>detection of foodborne pathogens was also forecasted. In 2017, our team has developed an approach</p><p>for detecting pathogens such as Salmonella, Vibrio parahaemolyticus, Vibrio cholerae and Listeria</p><p>monocytogenes by near-infrared immunoassay.</p> |
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| DOI: | 10.17352/2455-3492.000028 |