Research progress of near-infrared fl uorescence immunoassay

• मुख्य लेखकों: Xiao Hui Chang (लेखक), Jie Zhang (लेखक), Lin Huan Wu (लेखक), Yan Kun Peng (लेखक), Xiang Ying Yang (लेखक), Xiao Lin Li (लेखक), Ai Jin Ma (लेखक), Jun Cai Ma (लेखक), Guang Quan Chen (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: International Journal of Nanomaterials, Nanotechnology and Nanomedicine - Peertechz Publications, 2019-02-27.
• विषय: Review Article
• ऑनलाइन पहुंच: Connect to this object online.

<p>Near-infrared fl uorescence immunoassay has been widely studied in the bio analytical fi eld. This</p><p>review mainly introduces the basic principles of near-infrared spectroscopy and near-infrared detection</p><p>technology, and summarizes the properties, characteristics and recent improvement of optical properties</p><p>and signal intensity of three near-infrared fl uorescence probes (i.e. organic fl uorophores, quantum dots</p><p>and rare earth compounds). We describe the applications of near-infrared fl uorescence technology in</p><p>immunoassay, and prospect the application potential of lateral fl ow assay (LFA) based on this probe in</p><p>the rapid detection of pathogens. Our team intends to establish a new platform which has highly sensitive</p><p>near-infrared fl uorescence probes (NIFPs) combined with portable and simple immunochromatographic</p><p>test strips (ICTSs) for rapid detection of food borne viruses. This will provide technical support for a rapid</p><p>detection on the port.</p><p>Practical applications</p><p>The applications of near-infrared fl uorescence probes (NIFPs) in immunological analysis and clinically</p><p>important biomarkers were also elaborated. Moreover, NIFPs-based immunoassay adaptable for rapid</p><p>detection of foodborne pathogens was also forecasted. In 2017, our team has developed an approach</p><p>for detecting pathogens such as Salmonella, Vibrio parahaemolyticus, Vibrio cholerae and Listeria</p><p>monocytogenes by near-infrared immunoassay.</p>