Hepatotoxicity after Sevoflurane Exposure in a Patient with Chronic Hepatitis C
<p>Sevoflurane is considered a safe inhaled anesthetic of choice in patients with liver disease. Compared to other halogenated inhaled anesthetics, Sevoflurane is reported to lessen the severity of decreased hepatic blood flow and undergoes a different mechanism of hepatic metabolism. In patie...
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Global Journal of Medical and Clinical Case Reports - Peertechz Publications,
2015-12-17.
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LEADER | 00000 am a22000003u 4500 | ||
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001 | peertech__10_17352_2455-5282_000021 | ||
042 | |a dc | ||
100 | 1 | 0 | |a Nickul N Shah |e author |
700 | 1 | 0 | |a Nina Ballone |e author |
700 | 1 | 0 | |a Raul Zamora |e author |
700 | 1 | 0 | |a Peter DeVito |e author |
700 | 1 | 0 | |a Samuel Wilson |e author |
245 | 0 | 0 | |a Hepatotoxicity after Sevoflurane Exposure in a Patient with Chronic Hepatitis C |
260 | |b Global Journal of Medical and Clinical Case Reports - Peertechz Publications, |c 2015-12-17. | ||
520 | |a <p>Sevoflurane is considered a safe inhaled anesthetic of choice in patients with liver disease. Compared to other halogenated inhaled anesthetics, Sevoflurane is reported to lessen the severity of decreased hepatic blood flow and undergoes a different mechanism of hepatic metabolism. In patients with preexisting liver disease, there is potential for low-flow Sevoflurane to induce acute liver damage through other mechanisms. Limited data exists to guide clinical decision-making when quantifying the severity of cirrhosis in patients with hepatitis C and its relationship to anesthesia choice. Previous studies have found that exposure to general anesthesia during abdominal surgery may increase the risk of hepatorenal failure. This study has raised a concern that anesthetics may interfere with various hepatic functions secondary to viral infection. The generation of abnormal liver enzymes and hypercoagulation has provided further exploration for such toxicity.</p> | ||
540 | |a Copyright © Nickul N Shah et al. | ||
546 | |a en | ||
655 | 7 | |a Case Report |2 local | |
856 | 4 | 1 | |u https://doi.org/10.17352/2455-5282.000021 |z Connect to this object online. |