Glimepiride induced Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH): A case report

<p>The Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) is an important cause of hyponatremia in hospitalized patients and can be caused by a variety of drugs. SIADH is a recognized side effect of 1st generation sulfonylurea (Chlorpropamide) due to its effect on vasopressin sec...

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主要な著者: Afia Zainab Tanni (著者), Md Farid Uddin (著者), Shohael Mahmud Arafat (著者), Shahjada Selim (著者), Marufa Mustari (著者), MSI Tipu Chowdhury (著者)
フォーマット: 図書
出版事項: Global Journal of Medical and Clinical Case Reports - Peertechz Publications, 2022-04-30.
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要約:<p>The Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) is an important cause of hyponatremia in hospitalized patients and can be caused by a variety of drugs. SIADH is a recognized side effect of 1st generation sulfonylurea (Chlorpropamide) due to its effect on vasopressin secretion. Here we described a 55-year-old woman with uncontrolled type 2 diabetes on glimepiride with SIADH presenting with anorexia, asthenia, and altered mental status. After the withdrawal of glimepiride, these symptoms were improved and sodium level returned to a normal value which demand monitoring of serum sodium level during treatment with glimepiride.</p>
DOI:10.17352/2455-5282.000151