Emergent of Colistin Resistant Enterobacteriaceae carrying the mcr-1 gene among clinical isolates from patients in an Argentine hospital: Clinical and microbiological aspects

• Main Authors: J Nievas (Author), D Torres (Author), F Nicola (Author), P Bonvehí (Author), L Scocozza (Author), W Alcalá (Author), F Herrera (Author), S Relloso (Author), J Smayevsky (Author)
• Format: Book
• Published: Global Journal of Infectious Diseases and Clinical Research - Peertechz Publications, 2018-12-11.
• Subjects: Letter to Editor
• Online Access: Connect to this object online.

Summary

<p>The recent emergence of multidrug-resistant (MDR) or extremely drug-resistant (XDR) Gram-negative bacteria has renewed interest in colistin (Polymyxins, a family of cationic polypeptide antibiotics) as a last-resort in the treatment of severe bacterial infections [1,2], despite being a drug with potential serious adverse events (mainly high risk of nephrotoxicity) [3,4]. Acquired resistance to polymyxins is generally associated with chromosomal mutations [5,6]. </p>

DOI

10.17352/2455-5363.000019