Addressing the treatment of macrophage activation syndrome: A challenging balance between immune suppression and infectious risk

<p>Hemophagocytic Lymphohistiocytosis (HLH) is a rare and potentially life-threatening syndrome related to a dysregulation of cytolytic function of Natural Killer (NK) cells and cytotoxic T cells (CTLs), which in turns leads to an inappropriate immune stimulation and hyperinflammatory state, r...

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Bibliographic Details
Main Authors: Vassia V (Author), Iannaccone A (Author), Marengo S (Author), Briozzo A (Author), Brussino A (Author), Alessi L (Author), Brussino L (Author), Norbiato C (Author)
Format: Book
Published: Global Journal of Infectious Diseases and Clinical Research - Peertechz Publications, 2022-08-13.
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100 1 0 |a Vassia V  |e author 
700 1 0 |a  Iannaccone A  |e author 
700 1 0 |a  Marengo S  |e author 
700 1 0 |a  Briozzo A  |e author 
700 1 0 |a  Brussino A  |e author 
700 1 0 |a  Alessi L  |e author 
700 1 0 |a  Brussino L  |e author 
700 1 0 |a Norbiato C  |e author 
245 0 0 |a Addressing the treatment of macrophage activation syndrome: A challenging balance between immune suppression and infectious risk 
260 |b Global Journal of Infectious Diseases and Clinical Research - Peertechz Publications,   |c 2022-08-13. 
520 |a <p>Hemophagocytic Lymphohistiocytosis (HLH) is a rare and potentially life-threatening syndrome related to a dysregulation of cytolytic function of Natural Killer (NK) cells and cytotoxic T cells (CTLs), which in turns leads to an inappropriate immune stimulation and hyperinflammatory state, resulting in hypercytokinemia, accumulation of activated lymphocytes and macrophages [1,2].</p><p><br></p> 
540 |a Copyright © Vassia V et al. 
546 |a en 
655 7 |a Case Report  |2 local 
856 4 1 |u https://doi.org/10.17352/2455-5363.000052  |z Connect to this object online.