Does Milk Intake Play a Specific Role in the Pathogenesis of Kidney Stones?

• Main Authors: Simone Brardi (Author), Tiziano Verdacchi (Author), Giorgio Paoletti (Author), Vanni Giovannelli (Author), Ennio Duranti (Author)
• Format: Book
• Published: Archives of Renal Diseases and Management - Peertechz Publications, 2016-11-01.
• Subjects: Research Article
• Online Access: Connect to this object online.

<p><strong>Background:</strong> Diet plays a key role in the pathogenesis of kidney stones. In particular, recent findings have advanced knowledge on the protective role of a high calcium diet. However, not much is known about the specific role played by milk intake in the pathogenesis of kidney stones compared with other dairy products, especially cheese.</p><p><strong>Methods:</strong> We conducted a retroactive case-controlled study on the eating pattern of 42 patients (29 males and 13 females) with kidney stones and 20 healthy controls (6 males and 14 females) in order to assess whether, among the various dietary factors, milk intake was involved. The entire cohort was asked to fill in a semi-quantitative questionnaire on eating habits.</p><p><strong>Results:</strong> Logistic regression analysis at the end of the backwards selection showed that only two variables, i.e. gender and milk intake, were significantly significant, and thus retained in the final model. Kidney stones were 8.6 fold more likely to develop in subjects who drank less than one cup of milk a day compared with those who consumed more. However, milk intake was not associated with gender and age. </p>