Metformin Associated Lactic Acidosis without Organ Dysfunction and Effective Treatment
<p>Metformin is an oral antidiabetic from biguanide class and is the first-line treatment option for type 2 diabetes mellitus (DM) [1]. Most common side effects of metformin include gastrointestinal system side effects such as abdominal cramp, diarrhea, nausea and vomiting [2]...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Book |
| Published: |
Archives of Renal Diseases and Management - Peertechz Publications,
2016-12-06.
|
| Subjects: | |
| Online Access: | Connect to this object online. |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | <p>Metformin is an oral antidiabetic from biguanide class and is the first-line treatment option for type 2 diabetes mellitus (DM) [1]. Most common side effects of metformin include gastrointestinal system side effects such as abdominal cramp, diarrhea, nausea and vomiting [2]. Lactic acidosis is a rare but fatal serious side effect of metformin and its incidence is found 9 in every 100.000 patient years [3]. Nevertheless, this side effect generally occurs in those who have organ dysfunction (kidney, liver, lung or heart dysfunction etc.) [3,4]. In general, it is not expected in those who have no organ dysfunction. In this article, a case of severe lactic acidosis due to metformin in a patient with type 2 DM without any organ dysfunction was presented. </p> |
|---|---|
| DOI: | 10.17352/2455-5495.000015 |