Renal-limited lupus-like glomerulonephritis
<p>In the setting of an IgG-dominant immune complex-mediated glomerulonephritis, there are multiple pathological fi ndings that strongly suggest the diagnosis of lupus nephritis (LN) including "full-house" immunofluorescence staining for IgG, IgM, IgA, C3 and C1, ex...
Saved in:
Main Authors: | , , , , |
---|---|
Format: | Book |
Published: |
Archives of Renal Diseases and Management - Peertechz Publications,
2017-09-23.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Summary: | <p>In the setting of an IgG-dominant immune complex-mediated glomerulonephritis, there are multiple pathological fi ndings that strongly suggest the diagnosis of lupus nephritis (LN) including "full-house" immunofluorescence staining for IgG, IgM, IgA, C3 and C1, extraglomerular immune deposits, combined mesangial, subendothelial and subepithelial immune deposits and the presence of endothelial tubuloreticular inclusions (TRI). If at the time of biopsy or during the period of follow-up, the patient displayed no extrarenal manifestations or serological evidence of systemic lupus erythematosus (SLE) it is denominate renal-limited lupus-like glomerulonephritis (RLLN) and there are reports both adults and children. Purpose of the study: Clinical features review of in the peer-reviewed academic literature.</p><p><strong>Results</strong></p><p><strong>Clinical features</strong></p><p> RLLN patients were more often male and they presented with lower-range erythrocyturia, more proteinuria and less complement consumption in the classical pathway than LN patients. </p> |
---|---|
DOI: | 10.17352/2455-5495.000029 |