Type-1.5 Diabetes Mellitus with Autoimmune Hypothyroidism: A Rare Combination
<p>Autoimmune hypothyroidism may associate with type-1 Diabetes mellitus (DM) is a well-known entity as polyglandular autoimmune syndrome type-3. Type-1.5 DM is also known as late onset autoimmune mediated diabetes mellitus of adulthood (LADA) describing as- patients with type-2 diabetic pheno...
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| मुख्य लेखकों: | , , |
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| स्वरूप: | पुस्तक |
| प्रकाशित: |
Global Journal of Obesity, Diabetes and Metabolic Syndrome - Peertechz Publications,
2016-12-28.
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| विषय: | |
| ऑनलाइन पहुंच: | Connect to this object online. |
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| सारांश: | <p>Autoimmune hypothyroidism may associate with type-1 Diabetes mellitus (DM) is a well-known entity as polyglandular autoimmune syndrome type-3. Type-1.5 DM is also known as late onset autoimmune mediated diabetes mellitus of adulthood (LADA) describing as- patients with type-2 diabetic phenotype based on age, not etiology combined with islet-cell antibodies and progressive β-cell failure, requiring life-time insulin therapy. Authors report a misdiagnosed type-2 diabetic since 3-years, of 35-years-male with known case of hypothyroidism had uncontrolled hyperglycemia, 12.7% glycosylated hemoglobin (HbA1C), 1.09ng/ml serum C-peptide and 26IU/ml glutamic acid decarboxylase (GAD) antibody, with anti-microsomal antibody titre of 827IU/ml and anti-thyroglobulin antibody titre of 130IU/ml, on 3 oral hypoglycemic agents. He was diagnosed as type-1.5 DM with autoimmune hypothyroidism. During 11-months of follow-up, after initiating insulin therapy patient had 6.7% HbA1C and normal thyroid function with oral thyroxin medication. So all young diabetic adults should evaluate for type-1.5 DM with autoimmune hypothyroidism.</p> |
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| डिजिटल ऑब्जेक्ट पहचानकर्ता: | 10.17352/2455-8583.000013 |