Obesity, Diabetes and Gastrointestinal Malignancy: The role of Metformin and other Anti-diabetic Therapy
<p>The association between Diabetes and cancer has been known for decades with obesity and insulin resistance being postulated as the main underlying risk factors for both disorders. With rise of the epidemic of obesity in the USA and around the globe, there has been a rise in diabetes that is...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Book |
| Published: |
Global Journal of Obesity, Diabetes and Metabolic Syndrome - Peertechz Publications,
2018-07-27.
|
| Subjects: | |
| Online Access: | Connect to this object online. |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
MARC
| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | peertech__10_17352_2455-8583_000032 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Michael Ashamalla |e author |
| 700 | 1 | 0 | |a Irini Youssef |e author |
| 700 | 1 | 0 | |a Mena Yacoub |e author |
| 700 | 1 | 0 | |a Apoorva Jayarangaiah |e author |
| 700 | 1 | 0 | |a Nikita Gupta |e author |
| 700 | 1 | 0 | |a Justina Ray |e author |
| 700 | 1 | 0 | |a Sadat Iqbal |e author |
| 700 | 1 | 0 | |a Regina Miller Joie Singh |e author |
| 700 | 1 | 0 | |a Samy I McFarlane |e author |
| 245 | 0 | 0 | |a Obesity, Diabetes and Gastrointestinal Malignancy: The role of Metformin and other Anti-diabetic Therapy |
| 260 | |b Global Journal of Obesity, Diabetes and Metabolic Syndrome - Peertechz Publications, |c 2018-07-27. | ||
| 520 | |a <p>The association between Diabetes and cancer has been known for decades with obesity and insulin resistance being postulated as the main underlying risk factors for both disorders. With rise of the epidemic of obesity in the USA and around the globe, there has been a rise in diabetes that is currently reaching epidemic proportions. Diabetes is known to be associated with increased risk of several types of malignancy including breast, cervical, pancreatic and colon cancer. In this review, we discuss the epidemic of obesity and its consequential epidemic of diabetes highlighting the pathophysiologic mechanisms of increased cancer in the diabetic population. We will then discuss the role of insulin therapy as well as other antidiabetic medications, particularly metformin that has been to be associated with lower risk as well as better survival with GI malignancies based on several studies including a study that was recently published by our group.</p> | ||
| 540 | |a Copyright © Michael Ashamalla et al. | ||
| 546 | |a en | ||
| 655 | 7 | |a Review Article |2 local | |
| 856 | 4 | 1 | |u https://doi.org/10.17352/2455-8583.000032 |z Connect to this object online. |