A Study of Glucosylceramide Synthase and Glycolytic Pathway Enzymes in Patients with Hypereosinophilia

• Main Authors: Lisa Redmond (Author), Paul Kennedy (Author), Colm Buckley (Author), Philip T Murphy (Author)
• פורמט: ספר
• יצא לאור: International Journal of Immunotherapy and Cancer Research - Peertechz Publications, 2017-03-31.
• נושאים: Research Article
• גישה מקוונת: Connect to this object online.

<p>Glucosylceramide synthase is the rate limiting enzyme in ceramide glycosylation and shifts the balance between ceramide and glycosphingolipids towards proliferation and survival of cancer cells. Increased glucose availability and glycolytic metabolism is preferentially used by cancer cells...