Successful Treatment of Annular Elastolytic Giant Cell Granuloma with Tranilast and Topical Glucocorticoid under the Strict Restriction of Sun Exposure

<p>Annular elastolylic giant cell granuloma (AEGCG) is a rare granulomatous skin disease characterized by loss of elastic fibers accompanied with elastophagocytosis by multinucleated giant cells. The clinical appearance shows annular and serpiginous plaques with hypopigmentation or skin atroph...

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Главные авторы: Hidetoshi Takahashi (Автор), Katsuhiko Satoh (Автор), Akiyoshi Takagi (Автор), Akemi Ishida-Yamamoto (Автор), Hajime Iizuka (Автор)
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Опубликовано: International Journal of Dermatology and Clinical Research - Peertechz Publications, 2015-08-24.
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042 |a dc 
100 1 0 |a Hidetoshi Takahashi  |e author 
700 1 0 |a  Katsuhiko Satoh  |e author 
700 1 0 |a  Akiyoshi Takagi  |e author 
700 1 0 |a  Akemi Ishida-Yamamoto  |e author 
700 1 0 |a  Hajime Iizuka  |e author 
245 0 0 |a Successful Treatment of Annular Elastolytic Giant Cell Granuloma with Tranilast and Topical Glucocorticoid under the Strict Restriction of Sun Exposure 
260 |b International Journal of Dermatology and Clinical Research - Peertechz Publications,   |c 2015-08-24. 
520 |a <p>Annular elastolylic giant cell granuloma (AEGCG) is a rare granulomatous skin disease characterized by loss of elastic fibers accompanied with elastophagocytosis by multinucleated giant cells. The clinical appearance shows annular and serpiginous plaques with hypopigmentation or skin atrophy. Ultraviolet irradiation, heat, or other unknown factors are supposed to induce pathogenic alternation [1]. The treatment for AEGCG remains unestablished and various therapeutic modalities including intralesional and systemic glucocorticoids, psoralen plus ultraviolet A irradiation, cryotherapy,retinoids, fumaric acid esters, pimecrolimus and minocycline are applied [2,3]. We report a case of AEGCG successfully treated with oral tranilast and topical glucocorticoid with sunscreens</p> 
540 |a Copyright © Hidetoshi Takahashi et al. 
546 |a en 
655 7 |a Letter to Editor  |2 local 
856 4 1 |u https://doi.org/10.17352/2455-8605.000006  |z Connect to this object online.