Stress and Glucose metabolism: A Review
<p>Stress is an inescapable fact of life. The perceived stress induces endocrine alterations characterized</p><p>by the activation of hypothalamo-pituitary-adrenal axis and sympathetic adreno-medullary axis. The</p><p>glucocorticoids and catecholamines which are secrete...
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| Main Authors: | , , |
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| Format: | Book |
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Imaging Journal of Clinical and Medical Sciences - Peertechz Publications,
2018-03-29.
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| Online Access: | Connect to this object online. |
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| Summary: | <p>Stress is an inescapable fact of life. The perceived stress induces endocrine alterations characterized</p><p>by the activation of hypothalamo-pituitary-adrenal axis and sympathetic adreno-medullary axis. The</p><p>glucocorticoids and catecholamines which are secreted in response to stress induce variations in the</p><p>physiology and behavior that help the individual to adapt to changing demands of the body. Glucocorticoids</p><p>are known to play a central role in inducing the stress related pathophysiology. These hormones induce</p><p>hypermetabolism in order to cope up with the increasing energy demands of the body. However when the</p><p>stress is persistent the body adapts itself to continuous demands and starts regulating the metabolism</p><p>at higher levels than the normal, termed as allostasis. This overwhelming load on the body will predispose</p><p>the individual for the development of diseases. This mini-review focuses on long term chronic stress</p><p>induced alterations in glucose metabolism and development of insulin resistance and glucose intolerance</p><p>as a result of long term allostatic regulation.</p> |
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| DOI: | 10.17352/2455-8702.000037 |