Assessment of the role of multimodality imaging for treatment volume definition of intracranial ependymal tumors: An original article

• Main Authors: Ferrat Dincoglan (Author), Omer Sager (Author), Selcuk Demiral (Author), Murat Beyzadeoglu (Author)
• Format: Book
• Published: Global Journal of Cancer Therapy - Peertechz Publications, 2021-07-06.
• Subjects: Research Article
• Online Access: Connect to this object online.

Summary

<p>Objective: Radiotherapy (RT) can be used for primary treatment, adjuvant therapy, or for salvage of recurrences of intracranial ependymal tumors. In recent years, there is a rising trend towards reducing the adverse effects of RT by incorporation of modernized techniques. Accurate and precise RT treatment volume is essential for optimization of treatment results. Herein, we evaluated irradiation target designation of intracranial ependymal tumors.</p><p>Materials and methods: In this study, irradiation target designation was assessed for intracranial ependymal tumors. RT target volume definition was evaluated with comparative analysis for patients receiving irradiation for intracranial ependymal tumors.</p><p>Results: Optimal target coverage and minimal exposure of normal tissues was prioritized in RT treatment planning. Ground truth target volume determination was done with meticulous assessment of physicians. As the primary result, it was found that the ground truth target voume was identical with target determination with Computed Tomography (CT)-Magnetic Resonance Imaging (MRI) fusion based planning. </p><p>Conclusion: Incorporation of MRI in target definition process should be suggested for improving accuracy and precision of target and treatment volume definition for successful radiotherapeutic management of intracranial ependymal tumors despite the need for further supporting evidence.</p>

DOI

10.17352/2581-5407.000041