A first comprehensive look at the order-disorder nature of RTK KIT native and carcinogenic targets

<p>Receptors Tyrosine Kinases (RTKs) act as sensors for extracellular ligands, the binding of which triggers dimerization, activation, and autophosphorylation of specific tyrosine (Y) residues in the Cytoplasmic Domain (CD). This leads to the recruitment and activation of multiple downstream s...

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Autors principals: Luba Tchertanov (Autor), Julie Ledoux (Autor)
Format: Llibre
Publicat: Global Journal of Cancer Therapy - Peertechz Publications, 2022-10-07.
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3rd Floor Main Library

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