Direct action antivirals are effective in the total eradication of HCV in renal transplants
<p><strong>Introduction</strong>: The main objective of our study was to analyze the effectiveness of antiviral treatment (conventional or with direct-acting antivirals (DAA)) for total eradication of Hepatitis C Virus (HCV) in kidney transplant (KT) recipients. DAA are known drugs...
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| Format: | Book |
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Annals of Antivirals and Antiretrovirals - Peertechz Publications,
2019-07-22.
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| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | peertech__10_17352_aaa_000005 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Teresa Olea |e author |
| 700 | 1 | 0 | |a Inmaculada Castillo |e author |
| 700 | 1 | 0 | |a Carlos Jiménez |e author |
| 700 | 1 | 0 | |a Javier Bartolomé |e author |
| 700 | 1 | 0 | |a María José Santana |e author |
| 700 | 1 | 0 | |a JA Quiroga |e author |
| 700 | 1 | 0 | |a Vicente Carreño |e author |
| 700 | 1 | 0 | |a Rafael Selgas |e author |
| 245 | 0 | 0 | |a Direct action antivirals are effective in the total eradication of HCV in renal transplants |
| 260 | |b Annals of Antivirals and Antiretrovirals - Peertechz Publications, |c 2019-07-22. | ||
| 520 | |a <p><strong>Introduction</strong>: The main objective of our study was to analyze the effectiveness of antiviral treatment (conventional or with direct-acting antivirals (DAA)) for total eradication of Hepatitis C Virus (HCV) in kidney transplant (KT) recipients. DAA are known drugs that are approved by FDA for clinical and preclinical</p><p>investigations. The effi cacy was analyzed by testing for the presence of HCV- ribonucleic acid (RNA) in the pellets obtained after ultracentrifugation of follow-up plasma samples and in peripheral blood mononuclear cells (PBMC) from patients with HCV infection who had achieved a sustained virological response (SVR). The safety, and the renal and hepatic repercussions of the antiviral treatment were also evaluated.</p> | ||
| 540 | |a Copyright © Teresa Olea et al. | ||
| 546 | |a en | ||
| 655 | 7 | |a Research Article |2 local | |
| 856 | 4 | 1 | |u https://doi.org/10.17352/aaa.000005 |z Connect to this object online. |